Giro da Saúde: exercise pill; robot that removes clots; WHO and monkeypox

The week was marked by promising health advances, including a diet pill, still in testing, that worked with rodents and a robot that moves through the lumen of blood vessels to “clean up” clots resulting from ‘a cerebral vascular accident. Follow the main highlights, now here at the Giro da Saúde!

The micro robot moves through the lumen of blood vessels to remove clots resulting from a stroke (Image: Ermal Tahiri/Pixabay)

Imagine a microscopic-sized robot capable of penetrating blood vessels in search of clots to dissolve. That’s the idea researchers at Purdue University came up with when creating a microdevice that cleans up accumulated blood in the brain after a stroke.

The new technique has been shown to be 86% effective in animals, especially pigs. It consists of a self-cleaning catheter that works thanks to a magnetically controlled microrobot. In tests, scientists were able to draw blood from the brains of six out of seven animals with the device, showing that the innovation is a promising advance in the treatment of strokes.

Umbilical cord stem cells save a child with pulmonary hypertension (Image: Doodlartdotcom/Pixabay)

German researchers have successfully developed a therapy to treat pulmonary arterial hypertension (PAH, or high blood pressure in the lungs) using umbilical cord stem cells. A 3-year-old child underwent experimental treatment with the technique and showed substantial improvement in his condition.

After five therapy sessions with an interval of six months, the child improved and had no adverse effects. According to the medical board involved in the research, the girl no longer has any limitations in her ability to exercise and has also grown and gained weight at a greater rate than in previous months. There was also an improvement in lung and heart function.

1 in 500 men have an extra X or Y chromosome (Image: claudioventrella/Envato Elements)

If you remember from biology class, you must know that most men have a pair of sex chromosomes (X and Y) in their cells, which determines that the individual comes into the world as a man. However, it can happen that some are born, instead of XY, with extra sex chromosomes, resulting in XXY or XYY cells. The condition, which was once thought to be rare, appears to be more common than previously thought.

After analyzing 200,000 samples from men registered at the UK Biobank, the UK’s gene bank, it turned out that the estimate had to be doubled, meaning that one in 500 men has a sex chromosome. additional.

Research also shows that XXY men have significantly less testosterone than XY men, three times more likely to have delayed puberty, and four times more likely to be infertile. The effects of an extra Y chromosome are less well understood, but XYY males tend to be larger in childhood and adulthood, but appear to have normal reproductive functions.

Monkeypox a global public health risk, according to the WHO (Image: Twenty20photos/Envato)

On Wednesday, the World Health Organization (WHO) said the global outbreak of monkeypox “poses a real risk to public health”. Now, a special committee intends to assess whether to declare the disease a “public health emergency of international concern”, like covid-19.

According to Hans Kluge, WHO regional director for Europe, the epicenter of the epidemic, “the longer the virus circulates, the more it spreads its reach and the stronger the base of the disease in non-endemic countries”. He adds that “governments, health partners and civil society must act urgently and together to control this epidemic”.

Kluge also said monkeypox is not a reason to cancel events, but an opportunity to use them to build commitment to the fight against the disease.

The Lac-Phe molecule promoted cumulative weight loss in mice (Image: BrianAJackson/Envato Elements)

A recent discovery may thrill many people with the idea of ​​losing a few pounds without needing to go to the gym: researchers from Baylor College of Medicine and Stanford School of Medicine, in collaboration with other institutions , have discovered a molecule in the blood produced during exercise that can, in the future, be synthesized into a pill to help with weight loss, inhibiting hunger.

These are the amino acid Lac-Phe, an essential molecule produced from lactate, a by-product of physical activity that causes muscle soreness after it is performed, and phenylalanine, an important amino acid in the formation of proteins (hence the name “lac” and “phe”). In the laboratory, tests on mice showed that high doses of Lac-Phe suppressed the food consumption of obese animals by 50%.

After 10 days, Lac-Phe cumulatively decreased food consumption in addition to body weight due to body fat loss and increased glucose tolerance. Now, it remains to be understood how Lac-Phe mediates the effects on the human body.

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